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What role does genetics play in cognitive health?

Genetics indeed plays a significant role in cognitive health. While lifestyle factors like diet and exercise are essential, our genetic makeup can influence our susceptibility to cognitive decline and neurodegenerative conditions such as Alzheimer's disease. Research has identified several genetic risk factors associated with cognitive health, including the APOE gene, which has different variants (alleles). The APOE ε4 allele, in particular, is linked to a higher risk of Alzheimer's disease.

However, genetics is not destiny. Lifestyle choices still matter. Even with genetic predispositions, adopting a brain-healthy lifestyle can mitigate risks and promote cognitive well-being. Understanding your genetic background can help tailor preventive strategies.


  1. Sleegers, K., & Van Broeckhoven, C. (2018). Genetic risk and genetic testing in Alzheimer's disease. In Alzheimer's Disease (pp. 279-290). Springer.

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